Increasing Access to Genetic Testing in Underserved Patients Using a Multilingual Conversational Agent

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study compares the experiences of people who receive information about genetic testing from a computer-generated character to patients who receive information from a human genetics healthcare provider. Patients with cancer are increasingly recommended for genetic testing as standard of care. Multiple factors contribute to low usage of genetic testing but for many patients the lack of access to genetic counseling and testing is an important and flexible factor. Lack of access is especially relevant to racial/ethnic minority patients and those living in non-metropolitan rural settings who are frequently cared for at safety-net hospitals with limited genetics services. Alternative delivery models are necessary to improve rates of access to genetic testing in patients with cancer. Health information technology is under used by genetics providers. A patient-facing relational agent (PERLA) will provide pre-test genetics education in both English and Spanish across two clinical settings to facilitate more timely access to genetic testing. Using the PERLA intervention may help researchers learn different ways to provide education about genetic testing to patients with cancer compared to usual care.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• Age \> 18 years old

• Diagnosed with least one of the following:

‣ Epithelial ovarian cancer

⁃ Exocrine pancreatic cancer

⁃ Metastatic or high or very high-risk prostate cancer

⁃ Breast cancer at or before age 50

⁃ Bilateral breast cancer

⁃ Triple negative breast cancer

⁃ Male breast cancer OR

⁃ Healthcare provider who treats patients with any of the above types of cancer

• Able to read and write in English or Spanish

• Able to provide informed consent

Locations
United States
California
USC / Norris Comprehensive Cancer Center
RECRUITING
Los Angeles
New York
University of Rochester
RECRUITING
Rochester
Contact Information
Primary
Charite Ricker, MS
ricker@usc.edu
323-409-7710
Time Frame
Start Date: 2023-10-24
Estimated Completion Date: 2028-10-24
Participants
Target number of participants: 800
Treatments
Experimental: Intervention Phase Arm A (PERLA)
Patients receive access to PERLA comprising pre-test genetics education and standard post-test provider-based genetic counseling over 20-60 minutes. .
Active_comparator: Intervention Phase Arm B (usual care)
Patients receive access to usual care pre- and post-test provider-based genetic counseling.
Sponsors
Leads: University of Southern California
Collaborators: Dana-Farber Cancer Institute, Northeastern University, National Cancer Institute (NCI)

This content was sourced from clinicaltrials.gov